Preheat the air fryer: Set it to 370°F (188°C) for 5 minutes. This helps the loaf start cooking right away.
Make a panade: In a large bowl, stir the breadcrumbs and milk. Let it soak for 2–3 minutes.
This keeps the meatloaf moist.
Add aromatics and seasonings: Mix in the egg, onion, garlic, ketchup, Worcestershire, mustard, salt, pepper, Italian seasoning, and parsley.
Fold in the beef: Add the ground beef and gently mix with your hands or a fork until just combined. Don’t overwork the mixture or the loaf will be dense.
Shape the loaf: Form a tight, even loaf about 7–8 inches long and 2–3 inches high. A slightly taller loaf stays juicier but may need a couple extra minutes.
Prepare the basket: Line the air fryer basket with a piece of parchment or foil with holes poked in it for airflow. Place the loaf on top.
Mix the glaze: In a small bowl, combine ketchup, brown sugar, Worcestershire, and vinegar.
Set aside.
Cook the first stage: Air fry the meatloaf at 370°F (188°C) for 15 minutes.
Glaze and continue: Brush half the glaze over the top and sides. Air fry another 10–12 minutes.
Check temperature: Use a thermometer inserted into the center. You’re aiming for 160°F (71°C).
If needed, cook 3–5 minutes more.
Final glaze: Brush on the remaining glaze and air fry 2 minutes to set.
Rest and slice: Let the meatloaf rest for 5–10 minutes before slicing. This keeps the juices inside.